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    THORACIC CAVITYTHORACIC CAVITY

    MEDIASTINUMMEDIASTINUM

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    MediastinumMediastinum

    Mediastinum = space between lungs.Mediastinum = space between lungs.

    Superior mediastinum:Superior mediastinum:

    Separated from inferior by horizontal planeSeparated from inferior by horizontal planebetween sternal angle and IV disc T4-T5.between sternal angle and IV disc T4-T5.

    Fig. 1.34, p 135.Fig. 1.34, p 135.

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    MediastinumMediastinum

    Inferior:Inferior:

    Anterior:Anterior:

    Middle:Middle:

    Posterior:Posterior:

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    Superior MediastinumSuperior Mediastinum

    Retrosternal:Retrosternal:

    Great vessels and branches.Great vessels and branches.

    Thymus.Thymus.

    Prevertebral:Prevertebral:TracheaTrachea

    EsophagusEsophagus

    Thoracic ductThoracic ductSympathetic trunksSympathetic trunks

    Vagus nervesVagus nerves

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    Inferior MediastinumInferior Mediastinum

    Anterior:Anterior:

    Thymus, fat, lymph nodesThymus, fat, lymph nodes

    Middle:Middle:PericardiumPericardium

    Phrenic nervesPhrenic nerves

    Pericardiacophrenic arteryPericardiacophrenic artery

    Heart and great vesselsHeart and great vessels

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    Inferior MediastinumInferior Mediastinum

    Posterior:Posterior:

    EsophagusEsophagus

    Thoracic ductThoracic duct

    Aorta and branchesAorta and branches

    Vagus nervesVagus nerves

    Sympathetic trunksSympathetic trunks

    Azygos system of veinsAzygos system of veins

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    SUPERIOR MEDIASTINUMSUPERIOR MEDIASTINUM

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    ThymusThymus

    Occupies superior mediastinum on eitherOccupies superior mediastinum on either

    side of the midline.side of the midline.

    Behind manubrium.Behind manubrium.

    Covered by converging pleura of theCovered by converging pleura of the

    lungs.lungs.

    Involutes with fat after puberty.Involutes with fat after puberty.

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    ThymusThymus

    Blood supply:Blood supply:

    Anterior mediastinal arteries from internalAnterior mediastinal arteries from internal

    thoracic artery.thoracic artery.

    Inferior thyroid arteries from subclavianInferior thyroid arteries from subclavian

    artery.artery.

    Venous drainage:Venous drainage:

    Into left brachiocephalic vein.Into left brachiocephalic vein.

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    ThymusThymus

    Innervation:Innervation:

    Vagus nerve.Vagus nerve.

    Cardiac sympathetic plexus.Cardiac sympathetic plexus.

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    Middle Mediastinum (inferior)Middle Mediastinum (inferior)

    Pericardium:Pericardium:

    Encloses heart.Encloses heart.

    (Fig. 1.35, p 137).(Fig. 1.35, p 137).

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    Middle Mediastinum (inferior)Middle Mediastinum (inferior)

    Pericardium:Pericardium:

    Visceral (serous) (Fig 1.37, p 139):Visceral (serous) (Fig 1.37, p 139):

    = epicardium.= epicardium.

    Arterial mesocardium.Arterial mesocardium.

    Venous mesocardium.Venous mesocardium.

    Transverse sinus:Transverse sinus:

    Space between arterial and venousSpace between arterial and venous

    mesocardium.mesocardium.

    Oblique sinus:Oblique sinus:

    Space between right and left pulmonary veins.Space between right and left pulmonary veins.

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    Middle Mediastinum (inferior)Middle Mediastinum (inferior)

    Pericardium:Pericardium:

    Pericardial cavity.Pericardial cavity.

    Parietal (serous):Parietal (serous):

    Fused to fibrous pericardium.Fused to fibrous pericardium.

    Fibrous:Fibrous:

    Fused with central tendon of diaphragm:Fused with central tendon of diaphragm:

    Pericardiacophrenic ligament.Pericardiacophrenic ligament.

    Fused with sternum:Fused with sternum:

    Superior and inferior sternopericardialSuperior and inferior sternopericardial

    ligaments.ligaments.

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    POSTERIORPOSTERIOR

    MEDIASTINUMMEDIASTINUM

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    EsophagusEsophagus

    From base of neck to:From base of neck to:

    Left of midline to:Left of midline to:

    Midline to:Midline to:

    Left of midline.Left of midline.

    Passes through diaphragm at level of T10.Passes through diaphragm at level of T10.

    Lies:Lies:Behind trachea.Behind trachea.

    In front of vertebral column.In front of vertebral column.

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    Esophagus Blood SupplyEsophagus Blood Supply

    Bronchial artery.Bronchial artery.

    Thoracic aorta.Thoracic aorta.

    Left gastric artery.Left gastric artery.Left inferior phrenic artery.Left inferior phrenic artery.

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    Esophagus InnervationEsophagus Innervation

    Esophageal plexus:Esophageal plexus:

    Continuation of posterior pulmonary plexus.Continuation of posterior pulmonary plexus.

    Formed by right and left vagus nerves:Formed by right and left vagus nerves:

    Right vagus nerveRight vagus nerve posterior vagus nerve.posterior vagus nerve.

    Left vagus nerveLeft vagus nerve anterior vagus nerve.anterior vagus nerve.

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    Esophagus InnervationEsophagus Innervation

    Upper third:Upper third:

    Voluntary muscle.Voluntary muscle.

    Innervated by recurrent laryngeal nerve.Innervated by recurrent laryngeal nerve.

    Lower two-thirds:Lower two-thirds:

    Involuntary muscle.Involuntary muscle.

    Innervated by vagus and sympathetic chain.Innervated by vagus and sympathetic chain.

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    Left Thoracic ductLeft Thoracic duct

    Arises from cisterna chyli:Arises from cisterna chyli:

    At union of right and left lumbar trunks.At union of right and left lumbar trunks.

    Begins on the front of vertebral body T-12Begins on the front of vertebral body T-12

    or L-1.or L-1.

    Runs up through the thorax along the frontRuns up through the thorax along the front

    of the vertebral column.of the vertebral column.

    At first it lies to the right of midline.At first it lies to the right of midline.

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    Left Thoracic ductLeft Thoracic duct

    It moves over to the left side when itIt moves over to the left side when it

    reaches level T-5.reaches level T-5.

    Receives most of lymph from body belowReceives most of lymph from body below

    diaphragm.diaphragm.

    Drains left side of thoracic cavity and partDrains left side of thoracic cavity and part

    of right.of right.

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    Left Thoracic ductLeft Thoracic duct

    Receives lymph from left internal jugularReceives lymph from left internal jugular

    lymph trunk.lymph trunk.

    Receives lymph from left subclavian lymphReceives lymph from left subclavian lymph

    trunk.trunk.

    Empties into venous system at junction of:Empties into venous system at junction of:

    Left internal jugular vein.Left internal jugular vein.

    Left subclavian vein.Left subclavian vein.

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    Right Thoracic ductRight Thoracic duct

    Drains upper right thoracic cavity, rightDrains upper right thoracic cavity, right

    upper extremity, and right side of headupper extremity, and right side of head

    and neck.and neck.

    Empties into venous system at junction of:Empties into venous system at junction of:

    Right internal jugular vein.Right internal jugular vein.

    Right subclavian vein.Right subclavian vein.

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    Thoracic Sympathetic ChainThoracic Sympathetic Chain

    Lies against neck of ribs andLies against neck of ribs and

    costovertebral junctions.costovertebral junctions.

    12 thoracic ganglia pairs:12 thoracic ganglia pairs:

    First one often fused with inferior cervicalFirst one often fused with inferior cervical

    ganglion:ganglion:

    Referred to as stellate ganglion collectively.Referred to as stellate ganglion collectively.

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    Thoracic Sympathetic ChainThoracic Sympathetic Chain

    Cervical ganglia:Cervical ganglia:

    Superior.Superior.

    Middle.Middle.

    Inferior.Inferior.

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    Thoracic Sympathetic ChainThoracic Sympathetic Chain

    The preganglionic sympathetic supply toThe preganglionic sympathetic supply tothe thoracic viscera are from T15.the thoracic viscera are from T15.

    The postganglionics are from:The postganglionics are from:

    Superior, middle, and inferior cervicalSuperior, middle, and inferior cervicalganglia.ganglia.

    T1-T5 paravertebral ganglia.T1-T5 paravertebral ganglia.

    They exit the chain as direct fibers andThey exit the chain as direct fibers andtravel downwards to enter the thorax:travel downwards to enter the thorax:

    As cardiopulmonary splanchnic nerves.As cardiopulmonary splanchnic nerves.

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    Thoracic Sympathetic ChainThoracic Sympathetic Chain

    The cardiopulmonary splanchnic nervesThe cardiopulmonary splanchnic nerves

    travel on their own and do not accompanytravel on their own and do not accompany

    other nerves or vessels.other nerves or vessels.

    Function:Function:

    Coronary artery dilation.Coronary artery dilation.

    Increase heart rate.Increase heart rate.

    Bronchodilation.Bronchodilation.

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    Splanchnic NervesSplanchnic Nerves

    Composed of preganglionic fibers andComposed of preganglionic fibers and

    visceral sensory fibers.visceral sensory fibers.

    Supply abdominal viscera.Supply abdominal viscera.

    Synapse in prevertebral ganglia.Synapse in prevertebral ganglia.

    Refer in text to Figure 1.41, page 63.Refer in text to Figure 1.41, page 63.

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    Splanchnic NervesSplanchnic Nerves

    Greater:Greater:

    T5-T9.T5-T9.

    Synapses in celiac ganglion.Synapses in celiac ganglion.

    Lesser:Lesser:

    T10-T11.T10-T11.

    Synapses in the superior mesentericSynapses in the superior mesenteric

    ganglion.ganglion.

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    Splanchnic NervesSplanchnic Nerves

    Least:Least:

    T12.T12.

    Synapses in the aorticorenal ganglion.Synapses in the aorticorenal ganglion.

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    Vagus NerveVagus Nerve

    Cranial nerve XCranial nerve X

    Major parasympathetic supply to thoracicMajor parasympathetic supply to thoracic

    and abdominal viscera.and abdominal viscera.

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    Course of Vagus NerveCourse of Vagus Nerve

    Parallel to esophagus:Parallel to esophagus:

    Innervates esophagusInnervates esophagus

    Passes posterior to root of lung on eachPasses posterior to root of lung on each

    side.side.

    Pierces diaphragm with esophagus.Pierces diaphragm with esophagus.

    Becomes gastric nerve.Becomes gastric nerve.Supplies viscera in thoracic cavity.Supplies viscera in thoracic cavity.

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    Vagus Nerve BranchesVagus Nerve Branches

    Cardiac branches to cardiac plexus.Cardiac branches to cardiac plexus.

    Pulmonary branches to pulmonary plexus.Pulmonary branches to pulmonary plexus.

    Esophageal branches to esophagealEsophageal branches to esophagealplexus.plexus.

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    Vagus Nerve BranchesVagus Nerve Branches

    Left recurrent laryngeal nerve from leftLeft recurrent laryngeal nerve from left

    vagus:vagus:

    Hooks around arc of aorta to left ofHooks around arc of aorta to left of

    ligamentum arteriosum.ligamentum arteriosum.

    Right recurrent laryngeal nerve from rightRight recurrent laryngeal nerve from right

    vagus:vagus:

    Hooks around subclavian artery.Hooks around subclavian artery.

    Therefore: arises in neck, not thorax.Therefore: arises in neck, not thorax.

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    Phrenic NervePhrenic Nerve

    Arises in neck from:Arises in neck from:

    Ventral rami of C3-5 (C4 = majorVentral rami of C3-5 (C4 = majorcontribution)contribution)

    Passes anterior to pulmonary root on eachPasses anterior to pulmonary root on eachside (only nerve to do so).side (only nerve to do so).

    Sole motor innervation to diaphragm.Sole motor innervation to diaphragm.

    Sensory fibers to pericardium, mediastinalSensory fibers to pericardium, mediastinalpleura, and pleural and peritonealpleura, and pleural and peritonealcoverings of diaphragm.coverings of diaphragm.

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    Phrenic NervePhrenic Nerve

    Pain via phrenic nerves usually referred toPain via phrenic nerves usually referred to

    base of neck and tip of shoulder.base of neck and tip of shoulder.

    Accompanied by pericardiacophrenicAccompanied by pericardiacophrenic

    arteries.arteries.

    Branches of internal thoracic arteriesBranches of internal thoracic arteries

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    Lymphatic DrainageLymphatic Drainage

    50 tracheobronchial lymph nodes :50 tracheobronchial lymph nodes :

    Some of the largest lymph nodes in theSome of the largest lymph nodes in thebody.body.

    Include:Include:ParatrachealParatracheal

    Superior tracheobronchialSuperior tracheobronchial

    Inferior tracheobroncialInferior tracheobroncial

    BronchopulmonaryBronchopulmonaryPulmonaryPulmonary

    Text: p 131, Fig. 1.32Text: p 131, Fig. 1.32

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    Lymph Drainage of Thoracic CavityLymph Drainage of Thoracic Cavity

    Parasternal nodes:Parasternal nodes:

    Lie behind sternum along course of internalLie behind sternum along course of internal

    thoracic artery.thoracic artery.

    Receive lymph from thoracic wall, upperReceive lymph from thoracic wall, upper

    anterior abdominal wall, and diaphragm.anterior abdominal wall, and diaphragm.

    Also receive significant amount of lymphAlso receive significant amount of lymph

    from mammary gland.from mammary gland.Dump into parasternal lymph channel.Dump into parasternal lymph channel.

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    Lymph Drainage of Thoracic CavityLymph Drainage of Thoracic Cavity

    Posterior intercostal nodes:Posterior intercostal nodes:

    Lie in posterior intercostal space betweenLie in posterior intercostal space between

    heads of ribs.heads of ribs.

    Receive lymph from thoracic wall andReceive lymph from thoracic wall and

    paravertebral regions.paravertebral regions.

    Drain into thoracic duct:Drain into thoracic duct:

    From left and lower right.From left and lower right.Drain into right lymphatic duct:Drain into right lymphatic duct:

    From upper right.From upper right.

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    Lymph Drainage of Thoracic CavityLymph Drainage of Thoracic Cavity

    Diaphragmatic nodes:Diaphragmatic nodes:

    Lie on upper surface of diaphragm.Lie on upper surface of diaphragm.

    Receive lymph from diaphragm, pericardium,Receive lymph from diaphragm, pericardium,

    upper surface of liver.upper surface of liver.

    Drain to parasternal and posteriorDrain to parasternal and posterior

    mediastinal nodes.mediastinal nodes.

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    Lymph Drainage of Thoracic CavityLymph Drainage of Thoracic Cavity

    Posterior mediastinal nodes:Posterior mediastinal nodes:

    Lie along esophagus and descendingLie along esophagus and descending

    thoracic aorta.thoracic aorta.

    Brachiocephalic nodes:Brachiocephalic nodes:

    Lie along brachiocephalic veins.Lie along brachiocephalic veins.

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    Lymphatic Drainage of ThoraxLymphatic Drainage of Thorax

    Lymph TrunksLymph Trunks

    Bronchiomediastinal lymph trunks receiveBronchiomediastinal lymph trunks receive

    lymph from:lymph from:

    Posterior mediastinal nodesPosterior mediastinal nodes

    Brachiocephalic nodesBrachiocephalic nodes

    Tracheobronchial nodesTracheobronchial nodes

    Parasternal nodesParasternal nodes

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    Lymphatic Drainage of ThoraxLymphatic Drainage of Thorax

    Thoracic DuctThoracic Duct

    Begins in abdomen on right side of midline.Begins in abdomen on right side of midline.

    Receives most of lymph from body belowReceives most of lymph from body below

    diaphragm.diaphragm.

    Drains left side of thoracic cavity and part ofDrains left side of thoracic cavity and part of

    right.right.

    Receives lymph from left internal jugularReceives lymph from left internal jugularlymph trunk.lymph trunk.

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    Lymphatic Drainage of ThoraxLymphatic Drainage of Thorax

    Thoracic Duct (cont.):Thoracic Duct (cont.):

    Receives lymph from left subclavian lymphReceives lymph from left subclavian lymph

    trunk.trunk.

    Empties into venous system at junction of:Empties into venous system at junction of:

    Left internal jugular vein.Left internal jugular vein.

    Left subclavian vein.Left subclavian vein.

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    Lymphatic Drainage of ThoraxLymphatic Drainage of Thorax

    Right Lymphatic Duct:Right Lymphatic Duct:

    Drains upper right thoracic cavity, right upperDrains upper right thoracic cavity, right upper

    extremity, and right side of head and neck.extremity, and right side of head and neck.

    Empties into venous system at junction of:Empties into venous system at junction of:

    Right internal jugular vein.Right internal jugular vein.

    Right subclavian vein.Right subclavian vein.