unidade acadêmica de medicina veterinária · 2017-06-13 · slide 1 ectima contagioso...

Universidade Federal de Campina GrandeCentro de Saúde e Tecnologia Rural

Unidade Acadêmica de Medicina Veterinária

ECTIMA CONTAGIOSO

Prof. Dr. Silvano Higino

13/06/2017 ECTIMA CONTAGIOSO 1

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Família Poxviridae


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EtiologiaDoença viral altamente contagiosa de ovinos ecaprinos caracterizada pelo desenvolvimento delesões crostosas na pele do focinho e lábios e,menos frequentemente, em outros locais;

Parapoxvirus;

Boqueira, dermatite labial contagiosa;

Zoonose ocupacional.


Fonte: www.farmpoint.com.br

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Etiologia

Sensibilidade: Luz, formalina, fenol, ácidos, calor 60º por30min;

Resistência - sobrevive em crostas por 11 meses, aprisco pormais de 1 ano após a retirada de animais doentes;

Estritamente dérmica.


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Epidemiologia

A doença afeta primariamente ovinos e caprinos;

Casos esporádicos foram relatados em bovinos e caninos;

As lesões são dolorosas, mas são benignas e somente emraras ocasiões ocorre uma reação sistêmica grave.


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Epidemiologia

A morbidade pode chegar a 100%, mas a mortalidade raramente

excede a 1%;

As mortes ocorrem, por invasão das larvas de moscas e bactérias

como Fusobacterium necrophorum, Dermatophilus congolensis e

Staphylococcus spp.;

Nesses casos, a mortalidade pode chegar a 50%.


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Patogenia

O vírus se multiplica com facilidade no epitélio da pele e das

mucosas da boca e do esôfago;

A pele intacta oferece uma barreira à penetração do vírus;

Para ocorrer a infecção é necessária a presença de pequenas abrasões

ou escarificações.


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Patogenia

A infecção ocorre somente quando ovírus penetra no estrato espinhoso daepiderme;

3 dias após a penetração háavermelhamento no local.


Fonte: https://static.todamateria.com.br/upload/55/71/55715e021cccf-pele-humana.jpg

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Patogenia

Solução de continuidade

Camada espinhosa

Codificação de proteína homóloga ao fator de

crescimento endotelial vascular

Vascularização nas lesões

Corpúsculos de Guarnieri

Multiplicação da epiderme

Aumento na queratina


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Patogenia

Lesões proliferativas da epiderme iniciam por aumento dasmitoses na camada germinativa;

Em três dias o epitélio triplica sua espessura normal. Nãohavendo complicações, a lesão regride completamente emcerca de 25 dias.


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Patogenia

Máculas e eritema;

Pápulas;

Transformação em pústulas;

Úlceras (3 a 7 dias);

Dessecam e originam crostas;

Pode ocorrer seu desprendimento com cicatrização ou

infecção secundária.


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Transmissão

Contato direto, fômites, pastagenscontaminadas;

Cordeiros infectados podem contaminaros tetos das ovelhas e, dessa maneira,disseminar o vírus a outro cordeiro damesma ovelha.



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Sinais clínicos

P.I. – 2 a 4 dias;

As primeiras lesões desenvolvem-se nanas comissuras labiais;



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Fonte: www.farmpoint.com.brFonte: www.farmpoint.com.br


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Fonte: www.farmpoint.com.brFonte: www.farmpoint.com.br

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Sinais clínicos

Daí, as lesões disseminam-se para o focinho, fossas nasais eao redor dos olhos;

Em casos mais graves, as lesões ocorrem nas gengivas,almofadinha dental, palato, língua, esôfago, virilha, axila,vulva, ânus, prepúcio e membros;

Convalescentes - sólida imunidade por 2 a 3 anos;


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Fonte: Mertens, L. 2013

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DiagnósticoSinais clínicos e epidemiologia;

A confirmação laboratorial não é usualmente necessária;

Observação das partículas virais (crostas) e corpúsculos de inclusão pelamicroscopia eletrônica (fibroblastos de embrião de galinha);

PCR.


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Fonte: en.wikipedia.org

Fonte: en.wikipedia.org Fonte: en.wikipedia.org

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Tratamento

Não há tratamento específico;

As lesões podem ser tratadas com uso tópico de soluções de sulfato

de cobre a 5% e iodo a 7%;

As infecções secundárias podem ser tratadas com antibióticos;

Quando os surtos ocorrem em épocas de miíases, é recomendável o

uso de repelentes.


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Controle e profilaxia

A profilaxia é realizada através de vacinação anual;

A vacina é produzida com vírus vivo e seu uso introduz ovírus na propriedade;

Por isso a vacinação não deve ser usada em rebanhos ondenunca ocorreu a doença;


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Via de Administração: Cutânea por escarificação da

pele;

Posologia: 1 gota da vacina reidratada;

Cordeiros: 1ª vacinação até 8 semanas de idade

Em zonas de alto risco: revacinar a cada 5 ou 6 meses;

Em zonas de baixo risco: única vacinação é suficiente;

Obs: não vacinar fêmeas 7 semanas antes do parto e não

vacinar ovelhas com cordeiros ao pé.


Fonte: http://country.cdn.cevaws.com/var/ezflow_site/storage/images/media/ceva-brazil/images/ectimavac/1039761-1-por-BR/ectimavac_medium.png

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Controle e profilaxia

A imunidade ocorre em 3 semanas após a vacinação e durapor 6-8 meses;

A vacina deve ser aplicada na axila para evitar que ainfecção se dissemine por lambedura;


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Epidemiologia e Dados recentes

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Obrigado!!!

www.profhigino.webnode.com


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unidade acadêmica de medicina veterinária · 2017-06-13 · slide 1 ectima contagioso...

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