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rev bras hematol hemoter. 2 0 1 4; 3 6(5) :309–310 Revista Brasileira de Hematologia e Hemoterapia Brazilian Journal of Hematology and Hemotherapy www.rbhh.org Editorial Official communique: Chikungunya virus - a press release of the Associac ¸ão Brasileira de Hematologia, Hemoterapia e Terapia Celular regarding the safety of transfusions and transplants Dante Langhi Júnior , Dimas Tadeu Covas, Celso Bianco, Ester Sabino, José Francisco Comenalli Marques, José Eduardo Levi, Nanci Alves Salles, Neiva Sellan Lopes Gonc ¸ales, Simone Kashima Comitê de Doenc ¸as Infecciosas Transmitidas por Transfusão, Associac ¸ão Brasileira de Hematologia, Hemoterapia e Terapia Celular, Rio de Janeiro, RJ, Brazil The number of cases of Chikungunya an alphavirus trans- mitted by the mosquitoes Aedes aegypti and Aedes albopictus, continues to grow. The outbreak began in the Caribbean in December 2013 and until the present nearly 305,000 suspected cases have been reported to the Pan American Health Orga- nization/World Health Organization (PAHO/WHO). A total of 4756 of these cases have been confirmed as Chikungunya infection according to a communiqué issued online by the PAHO/WHO on July 3, 2014. The Brazilian health authorities are attentive to the evolu- tion of the situation in the Caribbean, which is now considered an epidemic. The Associac ¸ão Brasileira de Hematologia e Hemoterapia (ABHH), through its Committee on Transfusion- Transmitted Infectious Diseases, is vigilant. According to the committee there is no reason to introduce any measures yet, though it is studying the evolution of the situation and the measures to prevent transmission by transfusion and trans- plantation taken by other countries during epidemics. No cases of Chikungunya transmission have been described after blood transfusions, however, there is concern due to the many similarities with West Nile virus and dengue Corresponding author at: Hemocentro da Santa Casa de São Paulo, Rua Marquês de Itu, 579, 01221-000 São Paulo, SP, Brazil. E-mail address: [email protected] (D. Langhi Júnior). virus, which have similar routes of transmission (mosquitoes and transfusion). The first signs of the disease begin to appear between 3 and 7 days after the mosquito bite. The infection causes high fever, joint and muscle pain, rash, and headache. The disease rarely causes death, but joint pain can last for months or even years in some cases. There is no specific treatment or vaccine to prevent infec- tion with this virus, which most often affects under 1-year-old children, adults over 65 years of age and individuals with chronic diseases such as diabetes, and hypertension. There were 260,000 clinical cases of Chikungunya in a pop- ulation of 770,000 during an epidemic that occurred on the French island of La Réunion in the Indian Ocean in 2006. At that time, the French government suspended blood collections and sent packed red blood cells from France. Platelets were col- lected locally by apheresis and treated to inactivate pathogens prior to transfusion. In 2007, a small outbreak occurred in the region of Emilia-Romagna, Italy. As in La Réunion, blood collections were suspended in the affected area and blood components http://dx.doi.org/10.1016/j.bjhh.2014.07.019 1516-8484/© 2014 Associac ¸ão Brasileira de Hematologia, Hemoterapia e Terapia Celular. Published by Elsevier Editora Ltda. All rights reserved.

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Page 1: Revista Brasileira de Hematologia e Hemoterapia · Brasileira de Hematologia e Hemoterapia Brazilian Journal of Hematology and Hemotherapy Editorial Official communique: Chikungunya

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rev bras hematol hemoter. 2 0 1 4;3 6(5):309–310

Revista Brasileira de Hematologia e HemoterapiaBrazilian Journal of Hematology and Hemotherapy

www.rbhh.org

ditorial

fficial communique: Chikungunya virus - a presselease of the Associacão Brasileira deematologia, Hemoterapia e Terapia Celular

egarding the safety of transfusions andransplants

ante Langhi Júnior ∗, Dimas Tadeu Covas, Celso Bianco, Ester Sabino,osé Francisco Comenalli Marques, José Eduardo Levi, Nanci Alves Salles,eiva Sellan Lopes Goncales, Simone Kashima

omitê de Doencas Infecciosas Transmitidas por Transfusão, Associacão Brasileira de Hematologia, Hemoterapia e Terapia Celular, Rio deaneiro, RJ, Brazil

prior to transfusion.In 2007, a small outbreak occurred in the region of

he number of cases of Chikungunya an alphavirus trans-itted by the mosquitoes Aedes aegypti and Aedes albopictus,

ontinues to grow. The outbreak began in the Caribbean inecember 2013 and until the present nearly 305,000 suspectedases have been reported to the Pan American Health Orga-ization/World Health Organization (PAHO/WHO). A total of756 of these cases have been confirmed as Chikungunyanfection according to a communiqué issued online by theAHO/WHO on July 3, 2014.

The Brazilian health authorities are attentive to the evolu-ion of the situation in the Caribbean, which is now consideredn epidemic. The Associacão Brasileira de Hematologia eemoterapia (ABHH), through its Committee on Transfusion-ransmitted Infectious Diseases, is vigilant. According to theommittee there is no reason to introduce any measures yet,hough it is studying the evolution of the situation and the

easures to prevent transmission by transfusion and trans-lantation taken by other countries during epidemics.

No cases of Chikungunya transmission have been

escribed after blood transfusions, however, there is concernue to the many similarities with West Nile virus and dengue

∗ Corresponding author at: Hemocentro da Santa Casa de São Paulo, RuE-mail address: [email protected] (D. Langhi Júnior).

ttp://dx.doi.org/10.1016/j.bjhh.2014.07.019516-8484/© 2014 Associacão Brasileira de Hematologia, Hemoterapiaeserved.

virus, which have similar routes of transmission (mosquitoesand transfusion).

The first signs of the disease begin to appear between 3 and7 days after the mosquito bite. The infection causes high fever,joint and muscle pain, rash, and headache. The disease rarelycauses death, but joint pain can last for months or even yearsin some cases.

There is no specific treatment or vaccine to prevent infec-tion with this virus, which most often affects under 1-year-oldchildren, adults over 65 years of age and individuals withchronic diseases such as diabetes, and hypertension.

There were 260,000 clinical cases of Chikungunya in a pop-ulation of 770,000 during an epidemic that occurred on theFrench island of La Réunion in the Indian Ocean in 2006. Atthat time, the French government suspended blood collectionsand sent packed red blood cells from France. Platelets were col-lected locally by apheresis and treated to inactivate pathogens

a Marquês de Itu, 579, 01221-000 São Paulo, SP, Brazil.

Emilia-Romagna, Italy. As in La Réunion, blood collectionswere suspended in the affected area and blood components

e Terapia Celular. Published by Elsevier Editora Ltda. All rights

Page 2: Revista Brasileira de Hematologia e Hemoterapia · Brasileira de Hematologia e Hemoterapia Brazilian Journal of Hematology and Hemotherapy Editorial Official communique: Chikungunya

oter.

310 rev bras hematol hem

were imported from unaffected regions. Recently Europeancountries have introduced questions for donor selection aboutpossible contact with the disease; donors who visited anyaffected region are deferred for 28 days. It is important to note

that the measures were taken a few weeks after the start ofthe epidemic and no cases of transmission were recorded.

The ABHH remains vigilant by monitoring the spread ofChikungunya virus. So far, it has not spread within Brazil; as

2 0 1 4;3 6(5):309–310

to date (7/7/2014) there are only 17 cases of suspected Chikun-gunya fever isolated in specific regions of the country. Of these,only two cases were confirmed in Rio de Janeiro.

Conflicts of interest

The authors declare no conflicts of interest.