Neurociencia do comportamentoDr. Efrain Olszewer

FAPES

NEUROCIENCIA DO COMPORTAMENTO

ESTUDA OS PRINCIPIOS QUE REGULAM AS ATIVIDADES ROTINEIRAS, E SUA RELAÇÃO COM A BIOQUIMICA, ANATOMIA, FISIOLOGIA E FISIOPÁTOLOGIA, ASSIM COMO A METODOLOGIA TERAPEUTICA NA PROCURA DO EQUILIBRIO.

Powerful Solutions for

Stress Management

World s #1 Health Problem

1983

2004

2002

Crianças nascidas após WTC 09/01

Cortisol menor na saliva Stress das mães

Sobreviventes do Holocausto Menor cortisol

Por conviver com pais deprimidos ou ansiosos

JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 2004

ESCOLA DE MEDICINA MOUNT SINAI (NY) E UNIVERSIDADE DE EDIMBURGO

Filhos de 187 mulheres grávidas após 11/09/01

Diminuíram peso e nível de cortisol baixo em saliva

Stress Is Everywherehttp://www.stress.org/problem.htm

43% of all adults suffer from stress

75-90% of all visits to primary care physicians are for stress-related complaints or disorders

Stress has been linked to all the leading causes of death:

– CVD, cancer, lung ailments, accidents, cirrhosis and suicide

Stress levels have escalated in children, teenagers, college students and the elderly

Depression affects about 12.4 million women in the United States each year

In America alone, over 6 million men have depression each year

The price of job stress is estimated at over $300 billion annually

Job stress - leading source of stress for adults – Accidents

– Absenteeism

– Employee turnover

– Diminished productivity

– Direct medical, legal and insurance costs

41% adults reported at least one substantial stress symptom post-9.11 and continue to worry about homeland security

Violence - an increasingly serious problem

Fed. Agency: National Institute for

Occupational Safety and Health (NIOSH)

http://www.cdc.gov/niosh/stresswk.html

How Can Stress Cause So Much Illness?

Selye’s General Adaptation Syndrome

The 3 Stages of Stress

Arousal– Rapid increases in catecholamines

– Slower increases of corticosteroids

Adaptation– Characterized by sustained increased levels of

corticosteroids and alarm molecules

– Altered glucose tolerance, blood pressure, thyroid hormone and sex hormone metabolism

Exhaustion– Degenerative diseases characterized by the

adverse influence of corticosteroids and alarm molecules"Without stress, there would be no life" - Hans Selye

COLESTEROL

METABOLISMO ESTERÓIDES

Progesterona

17 OH Progesterona

Androsterona Testosterona

Estrona Estradiol

Estriol

Pregnenolona17 OH

Pregnenolona

DHEA

Boro

Cortisol