zolpidem

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Reactions 1454 - 1 Jun 2013 Zolpidem First report of galactorrhoea: case report A 29-year-old woman developed galactorrhoea following treatment with zolpidem for insomnia. The woman received oral zolpidem 5mg every night for post traumatic stress disorder associated insomnia; she presented with breast tenderness with galactorrhoea, 2 months after starting zolpidem. Zolpidem was withdrawn; two weeks later, her galactorrhoea resolved. Subsequent tests showed a serum prolactin level of 15.67 mg/mL. Author comment: "In this report, we will describe a case of zolpidem-induced galactorrhea." De Jesus D, et al. Zolpidem-induced galactorrhea via gabaergic inhibition of dopamine: A case report. Psychosomatic Medicine 75: A137-A138, No. 3, Apr 2013. Available from: URL: http:// dx.doi.org/10.1097/01.psy.0000429452.16135.1b [abstract] - USA 803087256 » Editorial comment: A search of AdisBase, Medline and Embase did not reveal any previous case reports of galactorrhoea associated with zolpidem. The WHO ADR database contained 12 case reports of galactorrhea associated with zolpidem. 1 Reactions 1 Jun 2013 No. 1454 0114-9954/10/1454-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

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Page 1: Zolpidem

Reactions 1454 - 1 Jun 2013

★Zolpidem

First report of galactorrhoea: case reportA 29-year-old woman developed galactorrhoea following

treatment with zolpidem for insomnia.The woman received oral zolpidem 5mg every night for post

traumatic stress disorder associated insomnia; she presentedwith breast tenderness with galactorrhoea, 2 months afterstarting zolpidem. Zolpidem was withdrawn; two weeks later,her galactorrhoea resolved. Subsequent tests showed a serumprolactin level of 15.67 mg/mL.

Author comment: "In this report, we will describe a caseof zolpidem-induced galactorrhea."De Jesus D, et al. Zolpidem-induced galactorrhea via gabaergic inhibition ofdopamine: A case report. Psychosomatic Medicine 75: A137-A138, No. 3, Apr2013. Available from: URL: http://dx.doi.org/10.1097/01.psy.0000429452.16135.1b [abstract] - USA 803087256

» Editorial comment: A search of AdisBase, Medline andEmbase did not reveal any previous case reports ofgalactorrhoea associated with zolpidem. The WHO ADRdatabase contained 12 case reports of galactorrhea associatedwith zolpidem.

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Reactions 1 Jun 2013 No. 14540114-9954/10/1454-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved