Reactions 1454 - 1 Jun 2013

★Zolpidem

First report of galactorrhoea: case reportA 29-year-old woman developed galactorrhoea following

treatment with zolpidem for insomnia.The woman received oral zolpidem 5mg every night for post

traumatic stress disorder associated insomnia; she presentedwith breast tenderness with galactorrhoea, 2 months afterstarting zolpidem. Zolpidem was withdrawn; two weeks later,her galactorrhoea resolved. Subsequent tests showed a serumprolactin level of 15.67 mg/mL.

Author comment: "In this report, we will describe a caseof zolpidem-induced galactorrhea."De Jesus D, et al. Zolpidem-induced galactorrhea via gabaergic inhibition ofdopamine: A case report. Psychosomatic Medicine 75: A137-A138, No. 3, Apr2013. Available from: URL: http://dx.doi.org/10.1097/01.psy.0000429452.16135.1b [abstract] - USA 803087256

» Editorial comment: A search of AdisBase, Medline andEmbase did not reveal any previous case reports ofgalactorrhoea associated with zolpidem. The WHO ADRdatabase contained 12 case reports of galactorrhea associatedwith zolpidem.

1

Reactions 1 Jun 2013 No. 14540114-9954/10/1454-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved