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0 2,000 4,000 6,0000
1,000
2,000
3,000
4,000
5,000
P2X7
Membrane Proteome Array
No
rma
lize
d T
arg
et
Bin
din
g
�ŶƚĂŐŽŶŝƐƚ�D�ďƐ �ŐŽŶŝƐƚ�D�ď
-11 -10 -9 -80
20
40
60
80
100
MAb 3
MAb 1MAb 2
Log [MAb] (M)
No
rma
lize
d C
a2+ F
lux
(%)
0 60 120 1800
20406080
100120140
20 nM
5 nM
1.25 nM
0 nM
[MAb]
MAbadded
Time (sec)
Ca
2+ I
nfl
ux
(% O
ver
Bas
elin
e)