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Management of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) after Cytoreductive Surgery (CRS) 19-21 MARCH HAMBURG 2015 EUROPEAN SCHOOL OF PERITONEAL SURFACE ONCOLOGY

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Management of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) after Cytoreductive Surgery (CRS)

19-21 MARCHHAMBURG2015

EUROPEAN SCHOOL OF PERITONEAL SURFACE ONCOLOGY

Course directors Chair: Beate Rau, Charité Campus Mitte, Berlin, DE Co-Chair: Marcello Deraco, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, IT

Experts in the field Dario Baratti MD, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, IT

Tom Cecil MD, Basingstoke and North Hampshire Hospital, Basingstoke, UK

Olivier Glehen MD, Centre Hospitalier Lyon-Sud, Pierre Bénite, Lyon, FR

Gabriel Glockzin MD, University of Regensburg, Regensburg, DE

Santiago González-Moreno MD, MD Anderson Cancer Center, Madrid, ES

Ludwig K. Groebler MD, European Surgical Institute (ESI), Hamburg, DE

Jens Hartmann DVM, AKH, Celle DE

Maik Kilian MD, Charité Campus Mitte, Berlin, DE

Christhardt Köhler MD, Charité Campus Mitte, Berlin, DE

Shigeki Kusamura MD, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, IT

Massimo Milione MD, Institute of Pathology, Fondazione IRCCS Istituto Nationale Tumori, Milano, IT

Jörg Pelz MD, University of Wuerzburg, Wuerzburg, DE

Pompiliu Piso MD, St. John of God Hospital, Regensburg, DE

Paolo Proto MD, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, IT

Horst-Geunter Rau, Amperklinikum, Dachau, DE

Pascal Rousset MD, Centre Hospitalier Lyon-Sud, Pierre Bénite, Lyon, FR

Paul H. Sugarbaker MD, Washington Cancer Center, Washington, US

Peter Thuss-Patience MD, Charité Campus Virchow-Klinikum, Berlin, DE

Kurt Van der Speeten MD, Ziekenhuis Oost-Limburg, Genk, BE

Florent Wallet MD, Centre Hospitalier Lyon-Sud, Pierre Bénite, Lyon, FR

Victor J. Verwaal MD, The Netherlands Cancer Institute, Amsterdam, NL

Management of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) after Cytoreductive Surgery (CRS)

Aim of the Advanced CourseThe ESSO Advanced Course “Management of HIPEC after CRS” aims to discuss evidence-based clinical decision-making in the management of primary and secondary peritoneal cancer and will offer a multidisciplinary programme combining both practical aspects and theoretical problems.

Technical and clinical approaches will be revisited and updated. Presentations will include the state of the art and latest advancements, videos with tips and tricks by the experts in the field, and case reports.

Participants will perform cytoreductive surgery in small groups in the wet lab using several new technical devices with supervision by the experts. Therefore the workshop is limited to a small number of participants (first come – first serve).

Ideal Advanced Course Candidate• Senior residents (last two years of training)• Experienced consultant surgeons• Good in English, written and spoken

Educational Methods• Interdisciplinary approach• Plenary lectures• Workshops• Video discussions• Case reports• Hands on: several operations procedures in the operating room• Textbook and Video Atlas edited by Paul Sugarbaker offered by FARGO (Foundation for Applied Research in Gastrointestinal Oncology)

PartnershipsESSO acknowledges the collaboration of the European Surgical Institute (ESI) and the Berufsverband der Deutschen Chirurgen (BDC).

Course Venue European Surgical Institute Hummelsbütteler Steindamm 71 D - 22851 Norderstedt Tel. +49 (0)40-52 97 32 15Website: www.esi-online.de

Course AccommodationSteigenberger Hotel Treudelberg HamburgLemsahler Landstraße 45D-22397 HamburgTel. +49 40 608 22 0Fax +49 40 608 22 8888

Website: www.treudelberg.com

Course coordinationAna Galán European Society of Surgical Oncology (ESSO)Email. [email protected]

Application ProcedureApplication must include:• Complete Application Form, available at www.essoweb.org (education/projects & courses)• Short CV (maximum 2 pages)• Applications must be sent by e-mail to [email protected]

Participation feeThe participation fee is 800 EUR for members and 950 EUR for non-members. It includes the registration to the 2-day course, 2-nights accommodation, coffee breaks and lunches and a social dinner.

AccreditationAn application for accreditation has been submitted to the European Accreditation Council for CME (EACCME) of the European Union of Medical Specialists (UEMS).

Programme

Thursday 19 March

14:00-14:50 Introduction Beate Rau

14:50-16:50 Treatment principles for peritoneal surface malignancies: surgical approach and clinical-pathological pathway

Chairs Beate Rau - Marcello Deraco

14:50-15:20 Techniques of cytoreductive surgery with peritonectomy procedures (CRS) Paul Sugarbaker

15:20-15:35 Pharmacology of different techniques of Intraperitoneal drug administration; role of heat and carriers Kurt van de Speeken

15:35-15:50 HIPEC: different techniques and role of intra abdominal pressure Shigeki Kusamura

15:50-16:05 Clinical diagnostic pathway for PSM Dario Baratti

16:05-16:20 Pathological diagnostic pathway for PSM Massimo Milione

16:20-17:00 Coffee Break

17:00-18:45 Perioperative Management

Chairs Paul Sugarbaker - Tom Cecil

17:00-17:15 OR personnel safety related to HIPEC Jörg Pelz

17:15-17:30 Preoperative staging in peritoneal metastases: necessary and nice to have (morphologic exams and peritoneal carcinomatosis) Pascal Rousset

17:30-17:45 To speak the same language: PCI, CCR and PSS Gabriel Glockzin

17:45-18:00 Perioperative management of CRS and HIPEC: view of anaesthesiologist Paolo Proto

18:00-18:15 Prevention and management of postoperative general complications Florent Wallet

18:15-18:30 Prevention and management of postoperative surgical complications related to CRS and HIPEC Maik Kilian

18:30-18:45 How to start a new center for the treatment of PSM Shigeki Kusamura

08:30-17:30 Operation room: hands on

Tutors Dario Baratti, Tom Cecil, Marcello Deraco, Olivier Glehen, Gabriel Glockzin, Santiago González-Moreno, Jens Hartmann, Christhardt Köhler, Maik Kilian, Shigeki Kusamura, Jörg Pelz, Pompiliu Piso, Beate Rau, Horst-Geunter Rau, Paul Sugarbaker, Kurt Van Der Speeten, Vic Verwaal

08:30-08:40 Preparation for the hands on: anatomical structure in animal Ludwig K. Groebler

08:40-08:50 Debreefing from human to animal Beate Rau

08:40-11:05 Right upper abdomen • Right abdominal wall • Interenteric • Right diaphram arcus tendineum • Resection gastric surface • Bursa omentalis • Splenectomy • Pancreatic tail resection

11:05-11:25 Coffee Break

11:25-12:30 Left upper abdomen • Left abdominal wall • Left diaphram arcus tendineum • Resection of serosal surface of bowel mesenterium • Hepatoduodenal ligament • Cholecystectomy • Resection of small bowel • Triangle ligament • Morrison pouch

12:30-13:30 Lunch

13:30-14:30 Pelvic • Resection of omentum • Resection of serosal surface of bowel • Resection of peritoneal surface of the bladder • Lymph node preparation central mesenterical route

14:30-15:00 Coffee Break

15:00-15:30 Devices HIPEC open and devices HIPEC close

16:00-17:30 Discussion with the experts1

Friday 20 March

Saturday 21 March 2015

08:30-10:40 Frequent indications and systemic treatment

Chairs Pompiliu Piso - Santiago González-Moreno

08:30-08:50 Pseudomyxoma peritonei (particularities of CRS, HIPEC and CCR score) Tom Cecil

08:50-09:10 Malignant peritoneal mesothelioma and primay peritoneal carcinoma (particularities of CRS, HIPEC and CCR score) Marcello Deraco

09:10-09:30 Peritoneal metastases from ovarian cancer (particularities of CRS, HIPEC and CCR score) Christhardt Köhler

09:30-09:50 Peritoneal metastases from gastric cancer (particularities of CRS, HIPEC and CCR score) Santiago González-Moreno

09:50-10:10 Peritoneal metastases from colorectal cancer (particularities of CRS, HIPEC and CCR score) Vic Verwaal

10.10-10.30 Treatment options in peritoneal metastases from gastrointestinal origin: the medical oncology point of view Peter Thuss-Patience

10.30-10.40 Ongoing clinical trials on G.I. cancer Olivier Glehen

10:40-11:10 Coffee Break

11:10-13:00 Selection is the key ! Case reports (Videos)

Chairs Christhardt Köhler - Marcello Deraco

11:10-11:30 Selection criteria for CRS and HIPEC Pompiliu Piso

11:30-11:45 Case 1 (PCI, SCORE, strategy, prognosis) Colorectal Cancer Vic Verwaal

11:45-12:00 Case 2 (PCI, SCORE, strategy, prognosis) Ovarian Cancer Christhardt Köhler

12:00-12:15 Case 3 (PCI, SCORE, strategy, prognosis) Mesothelioma Dario Baratti

12:15-12:30 Case 4 (PCI, SCORE, strategy, prognosis) Gastric Cancer Jens Hartmann

12:30-13:00 Conclusions and end of the course

ESSO is grateful for the continuous support of its corporate sponsors

European Society of Surgical Oncology (ESSO)Avenue E. Mounier 83

B 1200 BrusselsTel: +32 (0)2 5373106Fax : +32 (0) 5390374

Email : [email protected] : www.essoweb.org

The advanced course is supported by:

pantone vollton coated 1805