in-vitro dzukharian munandar, prof. dr. apt. akhmad kharis

94

DAFTAR PUSTAKA

Abla, M.J., Singh, N.D., dan Banga, A.K., 2016. Role of Nanotechnology in Skin

Delivery of Drugs, dalam: Dragicevic, N. dan Maibach, H.I. (Editor),

Percutaneous Penetration Enhancers Chemical Methods in Penetration

Enhancement. Springer Berlin Heidelberg, Berlin, Heidelberg, hal. 1–13.

Abolmaali, S.S., Tamaddon, A.M., Farvadi, F.S., Daneshamuz, S., dan Moghimi,

H., 2011. Pharmaceutical Nanoemulsions and Their Potential Topical and

Transdermal Applications. Iranian Journal of Pharmaceutical Sciences, 7:

139–150.

Agnihotri, N., Soni, G.C., Chanchal, D.K., dan Tiwari, S., 2019. A scientific review

on nanoemulsion for targeting drug delivery system. International Journal

of Life Sciences and Review, 5: 16–29.

Agubata, C.O., Nzekwe, I.T., Obitte, N.C., Ugwu, C.E., dan Onunkwo, G.C., 2014.

Effect of Oil, Surfactant and Co-Surfactant Concentrations on the Phase

Behavior, Physicochemical Properties and Drug Release from Self-

Emulsifying Drug Delivery Systems. Journal of Drug Discovery

Development and Delivery, 1: 7.

Ahmed un Nabi, S.A., Sheraz, M.A., Ahmed, S., Mustaan, N., dan Ahmad, I., 2016.

Pharmaceutical Gels: a Review. RADS Journal of Pharmacy and

Pharmaceutical Sciences, 4: 40–48.

Ainurofiq, A. dan Choiri, S., 2018. Development and optimization of a

meloxicam/β-cyclodextrin complex for orally disintegrating tablet using

statistical analysis. Pharmaceutical Development and Technology, 23: 464–

475.

Al Hagbani, T., Altomare, C., Salawi, A., dan Nazzal, S., 2018. D-optimal mixture

design: Formulation development, mechanical characterization, and

optimization of curcumin chewing gums using oppanol® B 12 elastomer as

a gum-base. International Journal of Pharmaceutics, 553: 210–219.

Anand, K., Ray, S., Rahman, M., Shaharyar, A., Bhowmik, R., Bera, R., dkk., 2019.

Nano-emulgel: Emerging as a Smarter Topical Lipidic Emulsion-based

Nanocarrier for Skin Healthcare Applications. Recent Patents on Anti-

Infective Drug Discovery, 14: 1–14.

Andarina, R. dan Djauhari, T., 2017. Antioksidan dalam Dermatologi. JKK, 4: 39–

48.

Anderson, Mark.J. dan Whitcomb, P.J., 2015. DOE Simplified: Practical Tools for

Effective Experimentation, Third Edition, Third. ed. CRC Press, Taylor &

Francis Group, New York.

Formulasi dan Karakterisasi Nano-Emulsi Vitamin E dalam Basis Hidrogel serta Uji PelepasannyasecaraIn-VitroDZUKHARIAN MUNANDAR, Prof. Dr. apt. Akhmad Kharis Nugroho, M.Si; Dr. rer. nat. Ronny Martien, M.SiUniversitas Gadjah Mada, 2021 | Diunduh dari http://etd.repository.ugm.ac.id/

95

Anton, N. dan Vandamme, T.F., 2011. Nano-emulsions and Micro-emulsions:

Clarifications of the Critical Differences. Pharmaceutical Research, 28:

978–985.

AOAC, 1990. Official Methods of Analysis of The Association of Official Analytical

Methods, 15th Edition. ed. AOAC International, Arlington, USA.

Armstrong, N.A., 2006. Pharmaceutical Experimental Design and Interpretation,

Second Edition. ed. Taylor & Francis.

Astuti, I.Y., Marchaban, M., Martien, R., dan Nugroho, A.E., 2018. Physical

Characterization and Dissolution Study of Pentagamavunon-0 Loaded Self

Nano-Emulsifying Drug Delivery System. Indonesian Journal of

Pharmacy, 29: 60.

Badawy, S.I.F., Narang, A.S., LaMarche, K.R., Subramanian, G.A., Varia, S.A.,

Lin, J., dkk., 2016. Integrated Application of Quality-by-Design Principles

to Drug Product Development: A Case Study of Brivanib Alaninate Film–

Coated Tablets. Journal of Pharmaceutical Sciences, 105: 168–181.

Bali, V., Ali, M., dan Ali, J., 2010. Study of surfactant combinations and

development of a novel nanoemulsion for minimising variations in

bioavailability of ezetimibe. Colloids and Surfaces B: Biointerfaces, 76:

410–420.

Baloch, J., Sohail, M.F., Sarwar, H.S., Kiani, M.H., Khan, G.M., Jahan, S., dkk.,

2019. Self-Nanoemulsifying Drug Delivery System (SNEDDS) for

Improved Oral Bioavailability of Chlorpromazine: In Vitro and In Vivo

Evaluation. Medicina, 55: 210.

Basera, K., Bhatt, G., Kothiyal, P., dan Gupta, P., 2015. Nanoemulgel: A Novel

Formulation Approach for Topical Delivery of Hydrophobic Drugs. World

Journal of Pharmacy and Pharmaceutical Sciences, 4: 1871–1886.

Bhatia, S., 2016. Nanoparticles Types, Classification, Characterization, Fabrication

Methods and Drug Delivery Applications, dalam: Natural Polymer Drug

Delivery Systems. Springer International Publishing, Cham, hal. 33–93.

Bhatt, P. dan Madhav, S., 2011. A Detailed Review on Nanoemulsion Drug

Delivery System. International Journal of Pharmaceutical Sciences and

Research, 2: 2482–2489.

Bhattacharjee, S., 2016. DLS and zeta potential – What they are and what they are

not? Journal of Controlled Release, 235: 337–351.

Bobby, J.G., Amala, F.K., Jeny, S., Vinod, B., dan Sunil, C., 2017. A Review on

Self Emulsifying Nanoemulsion. Journal of Pharmaceutical Research, 1:

000123.


96

Bolton, S. dan Bon, C., 2009. Pharmaceutical Statistics: Practical and Clinical

Applications, Fifth Edition, Fifth Edition. ed. CRC Press.

Borman, P. dan Elder, D., 2018. Q2(R1) Validation of Analytical Procedures; Text

and Methodology, dalam: Teasdale, A., Elder, D., dan Nims, R.W. (Editor),

ICH Quality Guidelines: An Implementation Guide. John Wiley & Sons,

Inc., Hoboken, NJ, USA, hal. 127–166.

Brayfield, A. (Editor), 2014. Martindale: The Complete Drug Reference, 38th ed.

Pharmaceutical Press.

Brown, C.K., Friedel, H.D., Barker, A.R., Buhse, L.F., Keitel, S., Cecil, T.L., dkk.,

2011. FIP/AAPS Joint Workshop Report: Dissolution/In Vitro Release

Testing of Novel/Special Dosage Forms. Indian Journal of Pharmaceutical

Sciences, 73: 338–353.

Bruschi, M.L. (Editor), 2015. Mathematical models of drug release, dalam:

Strategies to Modify the Drug Release from Pharmaceutical Systems,

Woodhead Publishing Series in Biomedicine. Elsevier, UK, hal. 63–86.

Chime, S.A., Kenechukwu, F.C., dan Attama, A.A., 2014. Nanoemulsions —

Advances in Formulation, Characterization and Applications in Drug

Delivery, dalam: Sezer, A.D. (Editor), Application of Nanotechnology in

Drug Delivery. InTech, hal. 77–126.

Choiri, S., Sulaiman, T.N.S., dan Kuncahyo, I., 2014. Optimization and Acessing

The Influence of Xanthan Gum, Effervescent Components and Hardness on

Floatation Behaviour and Drug Release of Gastro-Floating Captopril

Tablet. Indonesian Journal of Pharmacy, 25: 255–264.

Dasgupta, N., Ranjan, S., Mundra, S., Ramalingam, C., dan Kumar, A., 2016.

Fabrication of Food Grade Vitamin E Nanoemulsion by Low Energy

Approach, Characterization and Its Application. International Journal of

Food Properties, 19: 700–708.

Date, A.A., Desai, N., Dixit, R., dan Nagarsenker, M.S., 2010. Self-

nanoemulsifying drug delivery systems: formulation insights, applications

and advances. Nanomedicine, 5: 1595–1616.

Deshpande, J.M. dan Shah, D.P.B., 2012. Formulation and Development pH

induced in-situ gelling system of an anti infective drug for sustained ocular

drug delivery 2: 7.

Desmukh, A.S., 2015. Recent Advances in Self-Emulsifying Drug Delivery

Systems. International Journal of Pharmaceutical Sciences and

Nanotechnology, 8: 2693–2697.


97

Dewi, C.C. dan Saptarini, N.M., 2016. Hidroksi Propil Metil Selulosa dan

Karbomer serta Sifat Fisikokimianya sebagai Gelling Agent. Farmaka, 14:

1–10.

Efiana, N.A., Nugroho, A.K., dan Martien, R., 2013. Formulasi Nanopartikel

Losartan dengan Pembawa Kitosan. Jurnal Ilmu Kefarmasian Indonesia,

11: 7–12.

Gaspar, D.P.R., 2012. 'A novel strategy to produce a drug delivery system for skin

regeneration', . Universidade Da Beira Interior, Covilhã.

Gautam, S. dan Singh, A.K., 2014. Self Nanoemulsifying Drug Delivery System -

A Noval Approach for Improving Bioavailability. Journal of Drug Delivery

and Therapeutics, 4: 33–38.

Gilaberte, Y., Prieto-Torres, L., Pastushenko, I., dan Juarranz, Á., 2016. Anatomy

and Function of the Skin, dalam: Nanoscience in Dermatology. Elsevier,

hal. 1–14.

Gupta, S., Chavhan, S., dan Sawant, K.K., 2011. Self-nanoemulsifying drug

delivery system for adefovir dipivoxil: Design, characterization, in vitro and

ex vivo evaluation. Colloids and Surfaces A: Physicochemical and

Engineering Aspects, 392: 145–155.

Gurpreet, K. dan Singh, S.K., 2018. Review of Nanoemulsion Formulation and

Characterization Techniques. Indian Journal of Pharmaceutical Sciences,

80: 781–789.

Hategekimana, J., Chamba, Moses.V.M., Shoemaker, C.F., Majeed, H., dan Zhong,

F., 2015. Vitamin E nanoemulsions by emulsion phase inversion: Effect of

environmental stress and long-term storage on stability and degradation in

different carrier oil types. Colloids and Surfaces A: Physicochemical and

Engineering Aspects, 483: 70–80.

Honary, S. dan Zahir, F., 2013. Effect of Zeta Potential on the Properties of Nano-

Drug Delivery Systems - A Review (Part 1). Tropical Journal of

Pharmaceutical Research, 12: 255–264.

Huber, L., 2007. Validation and Qualification in Analytical Laboratories, 2nd ed.

Taylor & Francis.

Jaiswal, M., Dudhe, R., dan Sharma, P.K., 2015. Nanoemulsion: an advanced mode

of drug delivery system. 3 Biotech, 5: 123–127.

Jeevana Jyothi, B. dan Sreelakshmi, K., 2011. Design and Evaluation of Self-

Nanoemulsifying Drug Delivery System of Flutamide. Journal of Young

Pharmacists, 3: 4–8.


98

Jivani, M.N., Patel, C.P., dan Prajapati, B.G., 2018. Nanoemulgel Innovative

Approach For Topical Gel Based Formulation. Research and Reviews on

Healthcare: Open Acces Journal, 1: 18–23.

Kadu, P.J., Kushare, S.S., Thacker, D.D., dan Gattani, S.G., 2011. Enhancement of

oral bioavailability of atorvastatin calcium by self-emulsifying drug

delivery systems (SEDDS). Pharmaceutical Development and Technology,

16: 65–74.

Kazi, M., Al-Swairi, M., Ahmad, A., Raish, M., Alanazi, F.K., Badran, M.M., dkk.,

2019. Evaluation of Self-Nanoemulsifying Drug Delivery Systems

(SNEDDS) for Poorly Water-Soluble Talinolol: Preparation, in vitro and in

vivo Assessment. Frontiers in Pharmacology, 10: 459.

Keen, M.A. dan Hassan, I., 2016. Vitamin E in dermatology. Indian Dermatology

Online Journal, 7: 311.

Khan, A.W., Kotta, S., Ansari, S.H., Sharma, R.K., dan Ali, J., 2015. Self-

nanoemulsifying drug delivery system (SNEDDS) of the poorly water-

soluble grapefruit flavonoid Naringenin: design, characterization, in vitro

and in vivo evaluation. Drug Delivery, 22: 552–561.

Koufaki, M., 2016. Vitamin E derivatives: a patent review (2010 – 2015). Expert

Opinion on Therapeutic Patents, 26: 35–47.

Krstić, M., Medarević, Đ., Đuriš, J., dan Ibrić, S., 2018. Self-nanoemulsifying drug

delivery systems (SNEDDS) and self-microemulsifying drug delivery

systems (SMEDDS) as lipid nanocarriers for improving dissolution rate and

bioavailability of poorly soluble drugs, dalam: Lipid Nanocarriers for Drug

Targeting. Elsevier, hal. 473–508.

Kumar, A., Ahuja, A., Ali, J., dan Baboota, S., 2012. Curcumin Loaded Nano

Globules for Solubility Enhancement: Preparation, Characterization and Ex

Vivo Release Study. Journal of Nanoscience and Nanotechnology, 12:

8293–8302.

Kuncahyo, I., Choiri, S., Fudholi, A., Martien, R., dan Rohman, A., 2019.

Assessment of Fractional Factorial Design for the Selection and Screening

of Appropriate Components of a Self-nanoemulsifying Drug Delivery

System Formulation. Advanced pharmaceutical bulletin, 9: 609–618.

Kuswahyuning, R., Grice, J.E., Moghimi, H.R., dan Roberts, M.S., 2015.

Formulation Effects in Percutaneous Absorption, dalam: Dragicevic, N. dan

Maibach, H.I. (Editor), Percutaneous Penetration Enhancers Chemical

Methods in Penetration Enhancement. Springer Berlin Heidelberg, Berlin,

Heidelberg, hal. 109–134.


99

Makadia, H.A., Bhatt, A.Y., Parmar, R.B., Paun, J.S., dan Tank, H.M., 2013. Self-

nano Emulsifying Drug Delivery System (SNEDDS): Future Aspects. Asian

Journal of Pharmaceutical Research, 3: 20–26.

Martien, R., Irianto, I.D.K., Farida, V., dan Sari, P., 2012. Perkembangan Teknologi

Nanopartikel sebagai Sistem Penghantaran Obat. Majalah Farmaseutik, 8:

133–144.

Mavon, A., Raufast, V., dan Redoulès, D., 2004. Skin absorption and metabolism

of a new vitamin E prodrug, δ-tocopherol-glucoside: in vitro evaluation in

human skin models. Journal of Controlled Release, 100: 221–231.

Michaels, A.J., 2012. 'Vitamin E and Skin Health', Linus Pauling Institute. URL:

https://lpi.oregonstate.edu/mic/health-disease/skin-health/vitamin-E

(diakses tanggal 6/1/2020).

Miller, J.N. dan Miller, J.C., 2005. Statistics and Chemometrics for Analytical

Chemistry, 5th ed. Pearson/Prentice Hall.

Moffat, A.C., Osselton, M.D., dan Widdop, B. (Editor), 2011. Clarke’s Analysis of

Drugs and Poisons: In Pharmaceuticals, Body Fluids and Postmortem

Material, Fourth Edition. ed. Pharmaceutical Press.

Mounika, M., Desu, P.K., dan Vanitha, K., 2019. A Review on Self Nano

Emulsifying Drug Delivery System. Trends in Pharmaceuticals and

Nanotechnology, 2: 12–23.

Nabi, Z., Tavakkol, A., Dobke, M., dan Polefka, T.G., 2000. Bioconversion of

Vitamin E Acetate in Human Skin, dalam: Thiele, J. dan Elsner, P. (Editor),

Oxidants and Antioxidants in Cutaneous Biology. Karger, Basel, hal. 175–

186.

Nafisi, S. dan Maibach, H.I., 2018. Skin penetration of nanoparticles, dalam:

Emerging Nanotechnologies in Immunology. Elsevier, hal. 47–88.

Nasr, A., Gardouh, A., Ghonaim, H., Abdelghany, E., dan Ghorab, M., 2016. Effect

of Oils, Surfactants and Cosurfactans on Phase Behaviour and

Physicochemical Properties of Self-Nanoemusifying Drug Delivery System

(SNEDDS) for Irbesartan and Olmesartan. International Journal of Applied

Pharmaceutics, 8: 13–24.

Niki, E. (Editor), 2019. Vitamin E: Chemistry and Nutritional Benefits. Royal

Society of Chemistry.

Niki, E. dan Abe, K., 2019. Vitamin E: Structure, Properties and Functions, dalam:

Vitamin E: Chemistry and Nutritional Benefits. Royal Society of Chemistry,

hal. 1–11.


100

Nugroho, A.K., 2013. Sediaan Transdermal: Solusi Masalah Terapi Obat. Pustaka

Pelajar, Yogyakarta, YK.

Nurfauziah, R. dan Rusdiana, T., 2018. Formulasi Nanoemulsi Untuk

Meningkatkan Kelarutan Obat Lipofilik. Farmaka, 16: 352–360.

Obitte, N.C., Ofokansi, K.C., Nzekwe, I.T., Esimone, C.O., dan Okoye, I.E., 2011.

Self-Nanoemulsifying Drug Delivery Systems Based on Melon Oil and its

Admixture with a Homolipid from Bos indicus for the Delivery of

Indomethacin. Tropical Journal of Pharmaceutical Research, 10: 299–307.

Papakostas, D., Rancan, F., Sterry, W., Blume-Peytavi, U., dan Vogt, A., 2011.

Nanoparticles in dermatology. Archives of Dermatological Research, 303:

533–550.

Parmar, K., Patel, J., dan Sheth, N., 2015. Self nano-emulsifying drug delivery

system for Embelin: Design, characterization and in-vitro studies. Asian

Journal of Pharmaceutical Sciences, 10: 396–404.

Parmar, N., Singla, N., Amin, S., dan Kohli, K., 2011. Study of cosurfactant effect

on nanoemulsifying area and development of lercanidipine loaded

(SNEDDS) self nanoemulsifying drug delivery system. Colloids and

Surfaces B: Biointerfaces, 86: 327–338.

Patel, J., Patel, A., Raval, M., dan Sheth, N., 2011. Formulation and development

of a self-nanoemulsifying drug delivery system of irbesartan. Journal of

Advanced Pharmaceutical Technology & Research, 2: 9–16.

Poland, C.A., Read, S.A.K., Varet, J., Carse, G., Christensen, F.M., dan Hankin,

S.M., 2013. Dermal Absorption of Nanomaterials; Part of the ”Better

Control of Nano” Initiative 2012-2015. The Danish Environmental

Protection Agency, Copenhagen K, Denmark.

Politis, S.N., Colombo, P., Colombo, G., dan M. Rekkas, D., 2017. Design of

experiments (DoE) in pharmaceutical development. Drug Development and

Industrial Pharmacy, 43: 889–901.

Pratiwi, L., Fudholi, A., Martien, R., dan Pramono, S., 2017. Self-nanoemulsifying

Drug Delivery System (Snedds) for Topical Delivery of Mangosteen Peels

(Garcinia Mangostana L.,): Formulation Design and In vitro Studies.

Journal of Young Pharmacists, 9: 341–346.

Prausnitz, M.R., Elias, P.M., Franz, T.J., Schmuth, M., Tsai, J.-C., Menon, G.K.,

dkk., 2012. Skin Barrier and Transdermal Drug Delivery, dalam:

Dermatology. Elsevier Health Sciences, hal. 2065–2073.


101

PubChem, 2020a. 'PubChem Compound Summary for CID 2117, DL-alpha-

Tocopherol acetate', PubChem, National Center for Biotechnology

Information. URL: https://pubchem.ncbi.nlm.nih.gov/compound/2117


PubChem, 2020b. 'PubChem Compound Summary for CID 86472, alpha-

Tocopherol acetate', PubChem, National Center for Biotechnology

Information. URL: https://pubchem.ncbi.nlm.nih.gov/compound/86472


PubChem, 2020c. 'PubChem Substance Record for SID 340520954, all-rac-alpha-

Tocopheryl Acetate', PubChem, National Center for Biotechnology

Information. URL:

https://pubchem.ncbi.nlm.nih.gov/substance/340520954 (diakses tanggal

4/9/2020).

Ramasahayam, B., Eedara, B.B., Kandadi, P., Jukanti, R., dan Bandari, S., 2015.

Development of isradipine loaded self-nano emulsifying powders for

improved oral delivery: in vitro and in vivo evaluation. Drug Development

and Industrial Pharmacy, 41: 753–763.

Rao, J., Decker, E.A., Xiao, H., dan McClements, D.J., 2013. Nutraceutical

nanoemulsions: influence of carrier oil composition (digestible versus

indigestible oil) on β-carotene bioavailability. Journal of the Science of

Food and Agriculture, 93: 3175–3183.

Ravichandran, V., Shalini, S., Sundram, K.M., dan Rajak, H., 2010. Validation of

Analytical Methods - Strategies & Importance. International Journal of

Pharmacy and Pharmaceutical Sciences, 2: 18–22.

Ravisankar, P., Naga Navya, Ch., Pravallika, D., dan Navya Sri, D., 2015. A

Review on Step-by-Step Analytical Method Validation. IOSR Journal Of

Pharmacy, 5: 7–19.

Rehman, F.U., Shah, K.U., Shah, S.U., Khan, I.U., Khan, G.M., dan Khan, A.,

2017. From nanoemulsions to self-nanoemulsions, with recent advances in

self-nanoemulsifying drug delivery systems (SNEDDS). Expert Opinion on

Drug Delivery, 14: 1325–1340.

Saberi, A.H., Fang, Y., dan McClements, D.J., 2013. Fabrication of vitamin E-

enriched nanoemulsions: Factors affecting particle size using spontaneous

emulsification. Journal of Colloid and Interface Science, 391: 95–102.

Saha, P., Goyal, A.K., dan Rath, G., 2010. Formulation and Evaluation of Chitosan-

Based Ampicillin Trihydrate Nanoparticles. Tropical Journal of

Pharmaceutical Research, 9: 483–488.


102

Sarker, A., Shimu, I.J., Tuhin, R.H., dan Raju, A.A., 2015. Nanoemulsion: An

excellent mode for delivery of poorly soluble drug through different routes.

Journal of Chemical and Pharmaceutical Research, 7: 966–976.

Savale, S.K., 2015. A Review - Self-Nanoemulsifying Drug Delivery System

(SNEDDS). International Journal of Research in Pharmaceutical and Nano

Sciences, 4: 385–397.

Savoye, I., Olsen, C.M., Whiteman, D.C., Bijon, A., Wald, L., Dartois, L., dkk.,

2018. Patterns of Ultraviolet Radiation Exposure and Skin Cancer Risk: the

E3N-SunExp Study. Journal of Epidemiology, 28: 27–33.

Schieber, M. dan Chandel, N.S., 2014. ROS Function in Redox Signaling and

Oxidative Stress. Current Biology, 24: R453–R462.

Sengupta, P. dan Chatterjee, B., 2017. Potential and future scope of nanoemulgel

formulation for topical delivery of lipophilic drugs. International Journal of

Pharmaceutics, 526: 353–365.

Seo, Y.G., Kim, D.H., Ramasamy, T., Kim, J.H., Marasini, N., Oh, Y.-K., dkk.,

2013. Development of docetaxel-loaded solid self-nanoemulsifying drug

delivery system (SNEDDS) for enhanced chemotherapeutic effect.

International Journal of Pharmaceutics, 452: 412–420.

Shah, P., Bhalodia, D., dan Shelat, P., 2010. Nanoemulsion: A pharmaceutical

review. Systematic Reviews in Pharmacy, 1: 24.

Shahba, A.A.-W., Mohsin, K., dan Alanazi, F.K., 2012. Novel Self-

Nanoemulsifying Drug Delivery Systems (SNEDDS) for Oral Delivery of

Cinnarizine: Design, Optimization, and In-Vitro Assessment. AAPS

PharmSciTech, 13: 967–977.

Sheshala, R., Anuar, N.K., Abu Samah, N.H., dan Wong, T.W., 2019. In Vitro Drug

Dissolution/Permeation Testing of Nanocarriers for Skin Application: a

Comprehensive Review. AAPS PharmSciTech, 20: 164.

Sheskey, P.J., Cable, C.G., dan Cook, W.G., 2017. Handbook of Pharmaceutical

Excipients, 8th Edition. ed. Pharmaceutical Press, London, UK.

Siepmann, J. dan Siepmann, F., 2013. Mathematical modeling of drug dissolution.

International Journal of Pharmaceutics, , Poorly Soluble Drugs 453: 12–

24.

Singh, B., Khurana, L., Bandyopadhyay, S., Kapil, R., dan Katare, O.O.P., 2011.

Development of optimized self-nano-emulsifying drug delivery systems

(SNEDDS) of carvedilol with enhanced bioavailability potential. Drug

Delivery, 18: 599–612.


103

Singhal, M., Khanna, S., dan Nasa, A., 2011. Cosmeceuticals for the Skin: An

Overview. Asian Journal of Pharmaceutical and Clinical Research, 4: 1–6.

Siswanto, A., Fudholi, A., Nugroho, A.K., dan Martono, S., 2015. In Vitro Release

Modeling of Aspirin Floating Tablets Using DDSolver. Indonesian Journal

of Pharmacy, 26: 94.

Song, J., Bi, H., Xie, X., Guo, J., Wang, X., dan Liu, D., 2013. Preparation and

evaluation of sinomenine hydrochloride in situ gel for uveitis treatment.

International Immunopharmacology, 17: 99–107.

Soni, G.C., Prajapati, S.K., dan Chaudhri, N., 2014. Self Nanoemulsion: Advance

Form of Drug Delivery Systems. World Journal of Pharmacy and

Pharmaceutical Sciences, 3: 410–436.

Sultana, S.S., Parveen, P., Rekha, M.S., Deepthi, K., Sowjanya, Ch., dan Devi, A.S.,

2014. Emulgel – A Novel Surrogate Approach for Transdermal Drug

Delivery System. Indo American Journal of Pharmaceutical Research, 4:

1462–1477.

Tiruwa, R., 2016. A review on nanoparticles – preparation and evaluation

parameters. Indian Journal of Pharmaceutical and Biological Research, 4:

27–31.

Tsakovska, I., Pajeva, I., Al Sharif, M., Alov, P., Fioravanzo, E., Kovarich, S., dkk.,

2017. Quantitative structure-skin permeability relationships. Toxicology,

387: 27–42.

USP, 2017. U.S. Pharmacopeia National Formulary 2018: USP41-NF36. United

States Pharmacopeial Convention Incorporated.

Vagni, S., Saccone, F., Pinotti, L., dan Baldi, A., 2011. Vitamin E Bioavailability:

Past and Present Insights. Food and Nutrition Sciences, 02: 1088–1096.

Walker, R.M., Decker, E.A., dan McClements, D.J., 2015. Physical and oxidative

stability of fish oil nanoemulsions produced by spontaneous emulsification:

Effect of surfactant concentration and particle size. Journal of Food

Engineering, 164: 10–20.

Yang, S.-G. dan Shin, H.-J., 2010. The Functional Behaviors of Cosurfactant in

Design of Self-Nanoemulsifying Drug Delivery Systems. Journal of

Pharmaceutical Investigation, 40: 263–267.

Ying, L.Q. dan Misran, M., 2017. Rheological and physicochemical

characterization of alpha-tocopherol loaded lipid nanoparticles in

thermoresponsive gel for topical application. Malaysian Journal of

Fundamental and Applied Sciences, 13: 248–252.


104

Yu, L.X., Amidon, G., Khan, M.A., Hoag, S.W., Polli, J., Raju, G.K., dkk., 2014.

Understanding Pharmaceutical Quality by Design. The AAPS Journal, 16:

771–783.

Zhang, Y., Huo, M., Zhou, J., Zou, A., Li, W., Yao, C., dkk., 2010. DDSolver: An

Add-In Program for Modeling and Comparison of Drug Dissolution

Profiles. The AAPS Journal, 12: 263–271.

Zhao, T., Maniglio, D., Chen, J., Chen, B., Motta, A., dan Migliaresi, C., 2015.

Design and optimization of self-nanoemulsifying formulations for

lipophilic drugs. Nanotechnology, 26: 125102.

Zuo, J., Gao, Y., Bou-Chacra, N., dan Löbenberg, R., 2014. Evaluation of the

DDSolver Software Applications. BioMed Research International, 2014:

e204925.

Zussman, J., Ahdout, J., dan Kim, J., 2010. Vitamins and photoaging: Do scientific

data support their use? Journal of the American Academy of Dermatology,

63: 507–525.


in-vitro dzukharian munandar, prof. dr. apt. akhmad kharis

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